Thursday, September 1

08:30 – 10:20 SYMPOSIUM
Trauma Hemorrhage: basic and therapeutic approaches

Chairs: Marc Maegele (Germany), Mark Lehnert (Germany)
08:30 – 08:50

Impact of hyperfibrinolysis in trauma and hemorrhage
Herbert Schöchl (Austria)

08:50 – 10:20 Free Communications 3
08:50 – 09:05 Time course of lactate clearance in trauma and its relevance to outcomes (Chana M.S.)
09:05 – 09:20 Complement activation by cathepsin during trauma (Denk S.)
09:20 – 09:35 Complement activation in polytrauma patients is mediated by massive activation of FSAP (factor seven activating protease) (Gallenmueller A.)
09:30 – 09:50 Demonstrating the human cytokine response to tissue damage after traumatic injury (Manson J.)
09:50 – 10:05 Rotational thromboelastometric (rotem®) test results in the emergency room predicts massive transfusion in major trauma patients (Schöchl H.)
10:05 – 10:20

Secondary inflammatory response is attenuated with omega-3 polyunsatured fatty acids administration, in a compression model of spinal cord injury (Paterniti I.)

10:20 – 11:35

New Investigator Awards Session
New Investigator Awards Committee:
Irshad Chaudry (USA), Yngvar Gundersen (Norway),
Helder Mota-Filipe (Portugal), Eddy Neugebauer (Germany),
Chris Thiemermann (UK)

10:20 – 11:35 Selected Communications
10:20 – 10:35 Neuronal and glial markers in microdialysate after traumatic and hypoxemic brain injury in rats (Mondello S.)
10:35 – 10:50 Intravenous sulfide for the treatment of murine blunt chest trauma-induced lung injury (Wagner F.)
10:50 – 11:05 Cracking septic brains: regional (dys)functions separate survivors from non-survivors (Weixelbaumer K.)
11:05 – 11:20 ROS formation under restrictive versus full reperfusion following hemorrhagic traumatic shock (Penzenstadler C.)
11:20 – 11:35

Trauma/hemorrhage preceding sepsis strongly alters organ-specific and outcome-dependent expression of PAI-1 (Raeven P.)

11:35 – 12:05





Coffee Break

12:05 – 13:55 SYMPOSIUM
Gaseous mediators and gas therapy
Chairs: Mihály Boros (Hungary), Peter Radermacher (Germany)
12:05 – 12:25

Pathogen sensing pathways in human stem cell-derived endothelial cells
Daniel M. Reed (UK), Jane Mitchell (UK)

12:25 – 13:55 Free Communications 4
12:25 – 12:40 Nuclear factor kappa b (NF Kappa B) activation increases after hemorrhage/resuscitation (h/r) in chronic alcoholic liver disease (Weber R.)
12:40 – 12:55 Complex role of poly (ADP-ribosyl)ation in shock and other oxidative stress-related pathologies (Virag L.)
12:55 – 13:10 Effects of apocynin, a NADPH-oxidase inhibitor, in contrast-induced nephropathy (Ahmad A.)
13:10 – 13:25 Mild redox imbalance activates Nrf2 transcription factor and protects endothelial cells from TNF-<alpha> damage (Speciale A.)
13:25 – 13:40 Sulfide-effects on mitochondrial respiration depend on temperature and cell type (Gröeger M.)
13:40 – 13:55 Time dependency of H2S-induced organ protection during long-term, resuscitated porcine hemorrhage (Bracht H.)
14:00 – 15:00

Lunch & Poster Session

15:00 – 17:35 SIRC-European Shock Society Joint Session
Heart failure: from pathogenetic mechanism to innovative therapy

Chairs: Emanuela Masini (Italy), Heinz Redl (Austria)
15:00 – 15:25 Pathogenetic mechanisms of heart failure
Isabella Tritto (Italy)
15:25 – 15:50 Predictive biomarkers of risk of myocardial infarction
Giulio Pompilio (Italy)
15:50 – 16:15 Arrhythmogenic mechanisms in heart failure
Alessandro Mugelli (Italy)
16:15 – 17:10 Enhanced survival and paracrine activity of bone marrow mesenchymal stem cells: impact on cell therapy of ischemic heart failure
Angelo Parini (France)
17:10 – 17:35

Conclusive remarks
Elisabetta Cerbai (Italy)

17:45 – 18:30

AGM of the European Shock Society
Chairs: Soheyl Bahrami (Austria), Salvatore Cuzzocrea (Italy)

20:00 Social Dinner and Awards Ceremony