Friday, September 2

08:30 – 10:30 SYMPOSIUM
New therapeutic targets for cardiovascular diseases

Chairs: Inge Bauer (Germany), Jane Mitchell (UK)
08:35 – 09:00

Cardiovascular inflammation
Fulvio D’Acquisto (UK)

09:00 – 10:30 Free Communications 5
09:00 – 09:15 Influence of complement C5a antagonist treatment on the hemodynamic complications of cardiac tamponade (Erces D.)
09:15 – 09:30 C5a and the cardiomyopathy of sepsis (Ward P.)
09:30 – 09:45 Experimental acute traumatic coagulopathy: initiated by hypoperfusion, modulated by the protein C (Frith D.)
09:45 – 10:00 Trauma induced secondary cardiac injury is associated with acute inflammation (De’ath H.)
10:00 – 10:15 Between trauma and sepsis: age/gender modulate post-traumatic cytokine response and define the odds for accurate prediction of septic deaths (Drechsler S.)
10:15 – 10:30

Hepatic mitochondrial respiration in resuscitated murine septic shock
(Matallo J.)

10:30 – 11:00

Coffee Break

11:00 – 12:50 SIF-European Shock Society Joint Session
Glucocorticoids, immune monitoring and toll-like receptors
Chairs: Markus Huber-Lang (Germany), Achille P. Caputi (Italy)
11:00 – 11:20

Molecular mechanism of glucocorticoids: role of GILZ
Carlo Riccardi (Italy)

11:20 – 13:05 Free Communications 6
11:20 – 11:35 Palmitoylethanolamide systemic treatment reduces spinal and supraspinal formalin-induced neuroinflammation and allodynia (Luongo L.)
11:35 – 11:50 Palmitoylethanolamide attenuates astrocyte activation and neuroinflammation in animal model of Alzheimer’s disease (Scuderi C.)
11:50 – 12:05 Hydrogen sulphide is an endogenous inhibitor of phosphodiesterase activity (Bucci M.)
12:05 – 12:20 Beneficial role of peroxisome proliferator-activated receptor-beta/delta in septic shock (Kapoor A.)
12:20 – 12:35 Delayed activation of peroxisome proliferator-activated receptor (PPAR)-b/d improves longterm survival in the mouse model of polymicrobial sepsis (Bush D.)
12:35 – 12:50

Beneficial effects of CR3294 onto murine acute pancreatitis development, via iNOS-related oxidative stress reduction (Galuppo M.)

13:00 – 14:00

Lunch & Poster Session

14:00 – 15:30

SYMPOSIUM
Preclinical animal models

Chairs: Enrico Calzia (Germany), Martin F. Osuchowski (Austria)

14:00 – 15:30 Free Communications 7
14:00 – 14:15 Ceramide formation in host response to polymicrobial infection and development of organ failure (Claus R.)
14:15 – 14:30 Inflammatory mediators cause hepatocyte dysfunction via endoplasmic reticulum failure (Duvigneau J.)
14:30 – 14:45 Acute alcohol intoxication preserves organ integrity and improves survival after hemorrhage/resuscitation (h/r) in vivo (Relja B.)
14:45 – 15:00 Deliberate hypothermia during resuscitated porcine hemorrhagic shock (Simon F.)
15:00 – 15:15 The modulatory effect of evodiamine on splenic dendritic cells in mice following trauma (Liang H.)
15:15 – 15:30

Matri-cellular CCN proteins are regulated in sepsis-induced organ failure (Hviid C.)

15:30 – 17:00


SYMPOSIUM
Therapeutic gene modulation

Chairs: Eddy Neugebauer (Germany), Joan Groeneveld (The Netherlands)


15:30 – 17:00 Free Communications 8
15:30 – 15:45 Bone-marrow derived mononuclear cells protect against multiple organ failure in hemorrhagic shock through an akt dependant pathway (Nandra K.)
15:45 – 16:00 Protection against sepsis-associated cholestasis despite aggravated hepatocellular injury by selective knock-out of phosphoinositide 3-kinase gamma (Recknagel P.)
16:00 – 16:15 A novel immunotherapy that prevents lethal pneumonia driven by multi-drug resistant Pseudomonas aeruginosa (Neville L.)
16:15 – 16:30 Pre-treatment with erythropoietin reduces organ failure in a rat model of thermal injury (Rocha J.)
16:30 – 16:45 Protective effects of a phosphatidylcholine-enriched diet in lipopolysaccharide-induced experimental neuroinflammation (Tokes T.)
16:45 – 17:00

Effects of anaesthetic preconditioning on microRNA expression levels in primary cardiomyocytes (Grievink H.)

18:30 – 20:30 Junior Mixer